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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
36.36
Human Site:
S199
Identified Species:
57.14
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
S199
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Chimpanzee
Pan troglodytes
XP_522662
337
39019
S199
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
S199
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Dog
Lupus familis
XP_867638
336
38749
S199
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
L272
D
Y
S
Y
L
R
Q
L
F
R
N
L
F
H
R
Rat
Rattus norvegicus
P97633
325
37477
N191
T
A
R
Y
A
S
I
N
A
H
L
G
I
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
S199
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Frog
Xenopus laevis
Q5BP74
415
47421
L272
D
Y
S
Y
L
R
Q
L
F
R
N
L
F
H
R
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
E230
Q
K
Y
E
R
I
S
E
K
K
M
S
T
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
S202
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Honey Bee
Apis mellifera
XP_393612
350
40282
S203
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Nematode Worm
Caenorhab. elegans
P42168
341
39018
S198
A
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
S213
A
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
E230
Q
K
Y
E
R
I
S
E
K
K
V
S
T
S
I
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
F333
T
D
N
K
S
E
T
F
N
K
I
K
L
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
N.A.
100
13.3
0
N.A.
100
100
100
93.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
20
N.A.
N.A.
100
33.3
13.3
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
7
0
0
7
0
0
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
0
0
0
0
0
0
0
0
60
60
0
0
0
% D
% Glu:
0
0
0
14
0
67
0
14
0
0
0
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
7
14
0
0
0
14
0
0
% F
% Gly:
0
0
0
60
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
60
0
0
0
0
0
0
0
7
0
0
0
14
0
% H
% Ile:
0
0
0
0
60
14
7
0
0
0
7
0
7
0
14
% I
% Lys:
0
14
0
7
0
0
0
0
14
20
0
7
0
0
0
% K
% Leu:
0
0
60
0
14
0
0
14
0
0
7
14
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
54
0
0
% M
% Asn:
0
0
7
0
0
0
0
7
7
0
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
14
0
0
0
0
0
74
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
0
14
14
0
0
60
74
0
0
0
0
14
% R
% Ser:
0
0
14
0
7
7
14
60
0
0
0
14
0
7
60
% S
% Thr:
14
0
0
0
0
0
7
0
0
0
0
0
14
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
14
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _